Dr. Mark Pagnano
Dr. Mark Pagnano is an orthopedic surgeon and Chair of Orthopedic Surgery at Mayo Clinic in Rochester, Minnesota, known for hip and knee replacement.
Dr. Mark W. Pagnano, MD
Dr. Mark Pagnano is an orthopedic surgeon practicing in Rochester, Minnesota. He is known for hip and knee replacement, including robot-assisted knee surgery.
Professor and Chair of the Department of Orthopedic Surgery at Mayo Clinic in Rochester, and a consultant in adult hip and knee reconstruction.
Joint replacement replaces worn hips and knees with implants, relieving pain and restoring mobility for people with arthritis. Orthopedic surgeons are medical doctors who treat conditions of the bones, joints, ligaments, tendons and muscles.
About Dr. Mark Pagnano
- Full Name: Mark W. Pagnano, MD
- Credentials: MD
- Specialty: Orthopedic surgery (American Board of Orthopaedic Surgery, 2000)
- Subspecialty: Adult hip and knee reconstruction
- Current Role: Chair, Department of Orthopedic Surgery, Mayo Clinic
- Languages: English
- Gender: Male
- New Patients: Mayo Clinic appointments are requested through Mayo Clinic
- Telehealth: Not confirmed
- NPI: Not captured in this verification. Look up the NPI number on the NPPES NPI Registry (npiregistry.cms.hhs.gov).
Address and Contact
Mayo Clinic
- City: Rochester, Minnesota
- Street Address and Phone: Not captured; request appointments through Mayo Clinic
Appointment requests can be sent through the Book An Appointment button on this page. Office hours and patient portal details are not listed here unless the practice publishes them. Contact details verified September 30, 2026.
Specialties and Education
His published areas of care and procedures include:
- Hip replacement
- Knee replacement
- Robot-assisted knee replacement
- Robot-assisted partial knee resurfacing
- Perioperative pain management and blood loss reduction in joint replacement
Education and Training
- Undergraduate: BA with distinction in Economics, Colby College, 1987
- Medical School: MD, George Washington University School of Medicine, 1991
- Internship and Residency: Orthopedic surgery, Mayo Graduate School of Medicine, 1992 and 1996
- Fellowship: Knee reconstruction, Insall-Scott-Kelly Institute for Orthopaedics and Sports Medicine, 1997
- Leadership Training: Wharton Executive Leadership (2015); Harvard Business School Authentic Leaders Development Program
Certifications, License and Affiliations
- Board Certification: American Board of Orthopaedic Surgery, 2000
- Academic Appointment: Professor of Orthopedic Surgery, Mayo Clinic College of Medicine and Science
- Other Role: Medical Director, Mayo Clinic Department of Marketing
Insurance
No current, verifiable list of accepted insurance plans was found for this doctor. Coverage is not assumed. Contact the practice or your insurance company to confirm coverage before scheduling an appointment.
Fees
Consultation fees, self-pay prices, payment methods and cancellation policy are not publicly listed. Ask the practice for current pricing when you book.
Professional Information
- Hip Society Aufranc Award and Stinchfield Award (2017); Stinchfield Award (2008)
- Knee Society Clinical Research Awards (2013 and 2014)
- Chair of the AAOS Instructional Course Committee
- Deputy Editor, Clinical Orthopaedics and Related Research
- Former Deputy Director, Mayo Clinic Center for Regenerative Medicine
- Featured in The New York Times, The Wall Street Journal and NPR
Reviews and Ratings
No verified platform rating with a review count was captured for this doctor at the time of verification. Find MD Health does not create its own rating or ranking.
Verification
Key details on this page were checked against the public sources below on September 30, 2026. Official hospital, university and society sources were used first.
Frequently Asked Questions
What is Dr. Mark Pagnano known for?
Dr. Mark Pagnano is known for hip and knee replacement, including robot-assisted knee surgery.
Where does Dr. Mark Pagnano practice?
He practices at Mayo Clinic in Rochester, Minnesota, where he chairs the Department of Orthopedic Surgery.
What does an orthopedic surgeon do?
An orthopedic surgeon is a medical doctor who diagnoses and treats conditions of the bones, joints, ligaments, tendons and muscles, including fractures, arthritis, sports injuries, spine problems and joint replacement surgery.
How can I book with Dr. Mark Pagnano?
Use the Book An Appointment button on this page to send a request. Confirm the office location, referral needs and availability before you visit.
Find MD Health Disclaimer
Provider location, specialty information, insurance participation, and availability may change. Confirm current details directly with Mayo Clinic.

Reviews
There are no reviews yet.